Center Director

Dr. Paula Cohen

Department of Biomedical Sciences,

College of Veterinary Medicine,

Cornell University,

Ithaca, NY 14853


TEL: 607.253.4301

FAX: 607.253.3578


Center Co-Director

Dr. Peter Schlegel

525 East 68th Street

Starr Pavilion, 9th floor / Brady Urologic Health Center

New York, New York 10065


TEL: 212.746.5491

FAX: 212.746.8425


Center Administrator

Ms. Elena Cestero

Department of Biomedical Sciences,

College of Veterinary Medicine,

Cornell University,

Ithaca, NY 14853

TEL: 607.253.3302

CRG News

First Annual Retreat

The First Annual CRG Retreat in Reproductive and Developmental Genomics was held at Cornell Ithaca on June 14th and 15th. Sponsored by the editorial board of Molecular Reproduction and Development (MRD), and by Wiley Press, this event attracted researchers from all over the NorthEast. For more details, see the website. A meeting review will be published in MRD by trainees in our Center.

Postdoctoral Fellowships Available
In conjunction with the NICHD training grant in Reproductive Genomics, the CRG is pleased to announce its annual competition for postdoctoral fellows. The competition closes March 1st, 2013. See our advert for details
Argonautes in the Testis
The Cohen and Grimson labs have recently demonstrated that two members of the Argonaute small RNA-binding family, AGO3 and AGO4, are required for normal meiotic initiation and progression. Loss of AGO4 results in premature initiation of meiosis in neonatal male mice, as well as a loss of silencing of key Y-linked genes. These studies, published in Developmental Cell in August 2012, are the first to implicate AGO proteins, and their RNA binding partners, in mammalian gametes.
Breast Cancer Gene Identified
Cancerous tumors contain hundreds of mutations, and finding these mutations that result in uncontrollable cell growth is like finding the proverbial needle in a haystack. As difficult as this task is, it’s exactly what a team of scientists from Cornell University, the University of North Carolina, and Memorial Sloan-Kettering Cancer Center in New York, headed by Dr. John Schimenti, have done for one type of breast cancer. In a report appearing in the journal Genetics, Dr. Schimenti and his collaborators show that mutations in a gene called NF1 are prevalent in more than one-fourth of all noninheritable or spontaneous breast cancers. For more information, see press release.